Enabled CloudFlare on this site, with nearly every optimization thing they offer. So far it's looking good, with an empty (browser) cache it takes a moment to load initial resources but after that subsequent page loads are near-instantaneous (click around to try this out). To get SSL properly working you have to get a Pro account. Recommended!
Update: Getting fishy numbers with Pingdom (over 2000 ms), although page load times from my own machines are ok (around 500 ms or so). Investigating…
Performace-wise, setting up Amazon CloudFront ("Custom Origin") in addition to WP Minify and WP Super Cache improved site response times a lot. Offloading static content to Amazon not only made those offloaded files load faster (because of Amazon's faster tubes) but this also reduced stress on our feeble-ish server on page load so that the document itself is returned faster. Load time is also more repeatable. Good stuff!
Note that CloudFront makes HTTP/1.0 requests and Apache may take some convincing in order to make it Gzip the 1.0 response.